abstract：:The prevalence of grade III or IV osteoarthritis was determined in 210 patients with chronic renal failure, of whom 94 were receiving chronic haemodialysis and 116 had functioning renal transplants. The prevalence of grade III or IV osteoarthritis was three times greater in patients under 65 than in a control populati...

journal_title：Annals of the rheumatic diseases

authors： Duncan IJ,Hurst NP,Sebben R,Milazzo SC,Disney A

更新日期：1990-06-01 00:00:00

abstract：:The relation of habitual knuckle cracking to osteoarthrosis with functional impairment of the hand has long been considered an old wives' tale without experimental support. The mechanical sequelae of knuckle cracking have been shown to produce the rapid release of energy in the form of sudden vibratory energy, much li...

journal_title：Annals of the rheumatic diseases

authors： Castellanos J,Axelrod D

更新日期：1990-05-01 00:00:00

abstract：:Phenotypic and genotypic characteristics of the peripheral blood mononuclear cells in nine patients with Felty's syndrome have been examined. One patient had an increased number and percentage of peripheral blood mononuclear cells with the phenotype CD3+ Leu-7+ CD16+ and showed a clonal rearrangement of the T cell rec...

journal_title：Annals of the rheumatic diseases

authors： Ahern MJ,Roberts-Thomson PJ,Bradley J,Story C,Seshadri P

更新日期：1990-02-01 00:00:00

abstract：:Expression of major histocompatibility complex (MHC) class II and other lymphocyte activation markers on peripheral blood and synovial fluid T lymphocytes from patients with rheumatoid arthritis (RA), psoriatic arthritis, and Reiter's syndrome were measured and the mean fluorescence intensities of these antigens were ...

journal_title：Annals of the rheumatic diseases

authors： Smith MD,Roberts-Thomson PJ

更新日期：1990-02-01 00:00:00

abstract：:Previous work has suggested that prior poor reproductive outcome may be a risk factor in rheumatoid arthritis (RA). A case-control study of 195 women with RA and 462 control women from two different sources is presented here. No increase in rates of spontaneous abortion was seen in the women with RA; indeed a protecti...

journal_title：Annals of the rheumatic diseases

authors： Spector TD,Silman AJ

更新日期：1990-01-01 00:00:00

abstract：:The prosthetic knee joint of a 64 year old woman with severe rheumatoid arthritis was found to be infected with Listeria monocytogenes. After treatment with intravenous antibiotics, symptoms gradually resolved. She subsequently received prolonged treatment with oral co-trimoxazole and 18 months later remained well. ...

journal_title：Annals of the rheumatic diseases

authors： Booth LV,Walters MT,Tuck AC,Luqmani RA,Cawley MI

更新日期：1990-01-01 00:00:00

abstract：:Two British secondary schools (one a specialist music school) were surveyed to assess the prevalence of upper limb pain among specialist music students compared with students in a regular school setting. Female students tended to report pain more often than male students, but for both significantly higher prevalence w...

journal_title：Annals of the rheumatic diseases

authors： Fry HJ,Rowley GL

更新日期：1989-12-01 00:00:00

abstract：:Short term immobilisation (seven days) of an antigen induced arthritic knee joint of the mouse led to attachment of polymorphonuclear leucocytes to the cartilage surface and severe cartilage damage. The events at the patellar cartilage surface were studied by scanning electron microscopy and compared with the changes ...

journal_title：Annals of the rheumatic diseases

authors： van Lent PL,Wilms FH,van den Berg WB

更新日期：1989-10-01 00:00:00

abstract：:This paper looks at the problem confronting a doctor evaluating a patient with anticentromere antibody who does not have evidence of disease along the spectrum from CREST (calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia) to progressive systemic sclerosis. Of 33 people with anti...

journal_title：Annals of the rheumatic diseases

authors： Goldman JA

更新日期：1989-09-01 00:00:00

abstract：:Osteocalcin is a non-collagenous bone matrix protein which is released into the circulation and can be measured by radioimmunoassay. Recent studies indicate that serum osteocalcin concentrations are a marker of bone formation. Because bone demineralisation is a common finding in patients with rheumatoid arthritis (RA)...

journal_title：Annals of the rheumatic diseases

authors： Pietschmann P,Machold KP,Wolosczuk W,Smolen JS

更新日期：1989-08-01 00:00:00

abstract：:Feverfew, reputed by folklore to be effective in arthritis, has in vitro properties that could be beneficial in the control of inflammatory disease. Forty one female patients with symptomatic rheumatoid arthritis received either dried chopped feverfew (70-86 mg) or placebo capsules once daily for six weeks. Allocation...

journal_title：Annals of the rheumatic diseases

authors： Pattrick M,Heptinstall S,Doherty M

更新日期：1989-07-01 00:00:00

abstract：:HLA types, especially HLA-DR3, are associated with the development of toxic reactions in patients with rheumatoid arthritis after treatment with gold or D-penicillamine. In this study, after treatment with sulphasalazine, leucopenia was observed in three patients, who all had a history of leucopenia after previous gol...

journal_title：Annals of the rheumatic diseases

authors： Bliddal H,Eiberg B,Helin P,Svejgaard A

更新日期：1989-07-01 00:00:00

abstract：:Platelet serotonin concentrations were measured in 43 patients with systemic sclerosis, in 11 patients with primary Raynaud's phenomenon, and in 38 normal controls. Patients with the CREST variant (calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia) had significantly lower platele...

journal_title：Annals of the rheumatic diseases

authors： Klimiuk PS,Grennan A,Weinkove C,Jayson MI

更新日期：1989-07-01 00:00:00

abstract：:Collagenase etching has been used to show the microstructure of bone from patients suffering from primary osteoporosis. Both polished and unpolished surfaces of trabecular bone from femoral heads were treated with collagenase solution before study in the scanning electron microscope. The polished surfaces show the min...

journal_title：Annals of the rheumatic diseases

authors： Mackie IG,Green M,Clarke H,Isaac DH

更新日期：1989-06-01 00:00:00

abstract：:Leucopenia appears to be a more frequent complication of sulphasalazine treatment in rheumatoid arthritis than in inflammatory bowel disease and poses a management problem. In this study leucopenia was found in 20 patients, 14 of whom were participating in prospective studies (252 patients), giving an incidence of 5.6...

journal_title：Annals of the rheumatic diseases

authors： Marabani M,Madhok R,Capell HA,Hunter JA

更新日期：1989-06-01 00:00:00

abstract：:The incidence of exacerbations in the disease course was investigated in 110 patients with systemic lupus erythematosus (SLE) who were studied prospectively at our institute for lupus research. At the time of disease onset and diagnosis the male patients were much older than the female patients (about 10 years); exace...

journal_title：Annals of the rheumatic diseases

authors： Swaak AJ,Nossent JC,Bronsveld W,van Rooyen A,Nieuwenhuys EJ,Theuns L,Smeenk RJ

更新日期：1989-06-01 00:00:00

abstract：:A new method is described for separating free 35SO4-- from 35SO4 labelled proteoglycans synthesised by rabbit articular chondrocytes cultured in the presence of excess 35SO4--. The procedure uses the low solubility product of barium sulphate to remove, by precipitation, free 35SO4-- from culture medium. Optimum recove...

journal_title：Annals of the rheumatic diseases

authors： Collier S,Ghosh P

更新日期：1989-05-01 00:00:00

abstract：:Two patients (one male, one female) with ankylosing spondylitis (AS) and IgA nephropathy are described. The female patient is the first reported case to have AS and IgA nephropathy concurrently. Contrary to previously reported cases, her renal manifestation preceded her rheumatic symptoms. It is suggested that women w...

journal_title：Annals of the rheumatic diseases

authors： Lai KN,Li PK,Hawkins B,Lai FM

更新日期：1989-05-01 00:00:00

abstract：:In a double blind, single observer, 48 week study the effects of sulphasalazine (2 g daily) and hydroxychloroquine (400 mg daily months 0-6, thereafter 200 mg daily) were compared in 60 patients with definite or classical rheumatoid arthritis. They had not been treated previously with second line drugs. The onset of r...

journal_title：Annals of the rheumatic diseases

authors： Nuver-Zwart IH,van Riel PL,van de Putte LB,Gribnau FW

更新日期：1989-05-01 00:00:00

abstract：:The prevalence of mild and severe radiological osteoarthritis was investigated in a random sample of 6585 inhabitants of a Dutch village. Radiographs were graded 0-4 according to the criteria described by Kellgren and Lawrence. The prevalence of radiological osteoarthritis increased strongly with age and was highest f...

journal_title：Annals of the rheumatic diseases

authors： van Saase JL,van Romunde LK,Cats A,Vandenbroucke JP,Valkenburg HA

更新日期：1989-04-01 00:00:00

abstract：:A case of pachydermoperiostosis characterised by the presence of finger clubbing, periostosis, sweating of hands and feet is described. Modifications of capillaroscopic pattern and of arteriovenous anastomoses are reported. The periungual border and finger tip tissue showed diffuse endothelial hyperplasia, hyalinosis,...

journal_title：Annals of the rheumatic diseases

authors： Matucci-Cerinic M,Cinti S,Morroni M,Lotti T,Nuzzaci G,Lucente E,di Lollo S,Ceruso M,Cagnoni M

更新日期：1989-03-01 00:00:00

abstract：:The effect of auranofin on human neutrophil (PMN) 5-lipoxygenase activity and leucotriene B4 (LTB4) chemotaxis was investigated. [1-14C]Arachidonic acid was incorporated into the purified cells until steady state conditions were obtained. After preincubations with serial dilutions of auranofin arachidonic acid release...

journal_title：Annals of the rheumatic diseases

authors： Elmgreen J,Ahnfelt-Rønne I,Nielsen OH

更新日期：1989-02-01 00:00:00

abstract：:The circulating levels of sialic acid (N-acetylneuraminic acid) and glycosaminoglycans (GAGs) were measured in 69 patients with spinal disorders of orthopaedic interest (ankylosing spondylitis 17, osteofluorosis 6, idiopathic backache 10, osteoarthrosis 16, osteoporosis 20). The serum GAG levels showed no statisticall...

journal_title：Annals of the rheumatic diseases

authors： Susheela AK,Das TK,Khurana JS,Jayaswal A,Dave PK

更新日期：1988-10-01 00:00:00

abstract：:Neutrophil chemiluminescence was determined in patients with active rheumatoid arthritis. Twelve patients were randomly assigned either to a diet high in polyunsaturated fatty acids supplemented with eicosapentaenoic and docosahexaenoic acids or to a diet high in saturated fatty acids. A correlation with clinical and ...

journal_title：Annals of the rheumatic diseases

authors： Magaro M,Altomonte L,Zoli A,Mirone L,De Sole P,Di Mario G,Lippa S,Oradei A

更新日期：1988-10-01 00:00:00

abstract：:A 49 year old man is described with a polyarticular arthritis. Synovial fluid aspirated from the knee joint showed monosodium urate monohydrate and calcium pyrophosphate dihydrate by polarised light microscopy. Additionally, diphosphonate binding and scanning electron microscopy with energy dispersive analysis showed ...

journal_title：Annals of the rheumatic diseases

authors： Halverson PB,Ryan LM

更新日期：1988-10-01 00:00:00

abstract：:Autonomic function assessed by tests of cardiovascular reflexes was studied in 25 patients with systemic sclerosis and 10 patients with primary Raynaud's phenomenon. A comparison was made with 13 normal healthy subjects. Significant abnormalities in the cardiovascular reflexes were found in systemic sclerosis, both in...

journal_title：Annals of the rheumatic diseases

authors： Klimiuk PS,Taylor L,Baker RD,Jayson MI

更新日期：1988-07-01 00:00:00

abstract：:The effect of two gold(I) compounds on stability of lysosomes in vitro was studied. Lysosomes from homogenates of rat kidney cortex were isolated by differential centrifugation. These lysosomes were incubated at 37 degrees C with widely varied concentrations of sodium aurothiomalate and sodium aurothiosulphate for 5, ...

journal_title：Annals of the rheumatic diseases

authors： Graabaek PM,Pedersen SM

更新日期：1988-06-01 00:00:00

abstract：:Adenosine deaminase activity was determined in paired samples of serum and synovial fluid taken from patients with rheumatoid arthritis (n = 12), reactive arthritis (n = 13), and osteoarthritis (n = 7), and the value of this investigation in the diagnosis of synovial swellings was assessed. Increased activity was foun...

journal_title：Annals of the rheumatic diseases

authors： Yuksel H,Akoğlu TF

更新日期：1988-06-01 00:00:00

abstract：:Cell electrophoresis identifies two main subpopulations of blood polymorphonuclear cells (PMNs), which in terms of the speed of their anodic migration are referred to as the fast and slow population. When blood PMNs from normal healthy subjects were incubated in medium containing 20% RA serum there was a decrease in t...

journal_title：Annals of the rheumatic diseases

authors： Brown KA,McCarthy D,Perry JD,Dumonde DC

更新日期：1988-05-01 00:00:00

abstract：:A 57 year old white man with aortic insufficiency and previously undiagnosed ankylosing spondylitis, who developed subacute bacterial endocarditis (SBE), is described. Emergency aortic valve replacement was necessary, and the aortic valve pathology showed diffusely fibrosed and thickened valve leaflets with bacterial ...

journal_title：Annals of the rheumatic diseases

authors： Hoppmann RA,Wise CM,Challa VR,Peacock JE

更新日期：1988-05-01 00:00:00

abstract：:Serum IgG antibodies to native and denatured human type II collagen (Col II) were measured using an enzyme linked immunosorbent assay (ELISA). One hundred and thirty one patients with various forms of arthritis such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PSA). Reiter's Syndrome...

journal_title：Annals of the rheumatic diseases

authors： Choi EK,Gatenby PA,McGill NW,Bateman JF,Cole WG,York JR

更新日期：1988-04-01 00:00:00

abstract：:The synovial surface in rabbit knees was examined by scanning electron microscopy (SEM) to define normal surface contour, cell shape, and interstitial exposure. Comparison was made between specimens excised before immersion fixation (I), fixed in situ by vascular perfusion (V) before excision, or fixed in situ under a...

journal_title：Annals of the rheumatic diseases

authors： McDonald JN,Levick JR

更新日期：1988-03-01 00:00:00

abstract：:One hundred and two rural patients and 100 urban patients with rheumatoid arthritis and osteoarthrosis and 203 age and sex matched controls were visited in their homes to evaluate their problems, needs, and expectations. Although one would expect disability to affect the mobility of a person, it was found that rural p...

journal_title：Annals of the rheumatic diseases

authors： Cornelissen PG,Rasker JJ,Valkenburg HA

更新日期：1988-02-01 00:00:00

abstract：:Antibody production in response to the primary immunogen bacteriophage phi X174 was investigated in 14 patients with previous yersinia arthritis (YA) and in 15 controls. HLA-B27 occurred in 10 patients with YA and in three controls. After primary and secondary immunisation the antibody responses were essentially simil...

journal_title：Annals of the rheumatic diseases

authors： Bucknall R,Leirisalo-Repo M,Laitinen O,Jones JV

更新日期：1987-12-01 00:00:00

abstract：:Fifteen consecutive patients with acute arthritis were studied. Careful culture and microscopy of swabs from mucosal sites were performed to examine the hypothesis that the acute tropical polyarthritis commonly seen in Zimbabwe is due to undiagnosed gonococcal infection. Rheumatic fever and Reiter's disease accounted ...

journal_title：Annals of the rheumatic diseases

authors： Stein CM,Hanly MG

更新日期：1987-12-01 00:00:00

abstract：:It is postulated that the mobile inflamed joint may be subject to cyclical ischaemic reperfusion injury. Xanthine oxidoreductase is an enzyme thought to contribute to oxidative reperfusion injury, and the detection of this activity in human synovium is described. Three normal and five rheumatoid tissues were assayed w...

journal_title：Annals of the rheumatic diseases

authors： Allen RE,Outhwaite JM,Morris CJ,Blake DR

更新日期：1987-11-01 00:00:00

abstract：:The immune response against two herpesviruses has been determined in sera and matched synovial fluids of patients with rheumatoid arthritis (RA) and compared with that of a healthy control population. The increased level of antibody to Epstein-Barr virus (EBV) induced antigens in patients with RA resembles the antibod...

journal_title：Annals of the rheumatic diseases

authors： Musiani M,Zerbini M,Ferri S,Plazzi M,Gentilomi G,La Placa M

更新日期：1987-11-01 00:00:00

abstract：:Sixteen patients with classic rheumatoid arthritis (RA) complicated by severe vasculitis were studied and compared with a matched control group of 16 RA patients without vasculitis. Seven of the patients with vasculitis died within 4 to 120 months (median 32 months) after developing vasculitic symptoms. Gangrene of di...

journal_title：Annals of the rheumatic diseases

authors： Geirsson AJ,Sturfelt G,Truedsson L

更新日期：1987-10-01 00:00:00

abstract：:One hundred acute geriatric inpatients were assessed to investigate the prevalence of shoulder disorders; 21 had symptoms due to shoulder disease. Conditions included supraspinatus tendinitis (five), chronic rotator cuff rupture (seven), frozen shoulder (two), glenohumeral osteoarthritis (two), apatite related shoulde...

journal_title：Annals of the rheumatic diseases

authors： Chard MD,Hazleman BL

更新日期：1987-09-01 00:00:00

abstract：:The viscosity of plasma (PV) was investigated in 27 outpatients with classical or definite rheumatoid arthritis (RA) according to the American Rheumatism Association (ARA) criteria. The measurements showed a significantly raised PV in patients with RA (p less than 10(-5)) compared with a control group. There was a pos...

journal_title：Annals of the rheumatic diseases

authors： Harreby M,Danneskiold-Samsøe B,Kjer J,Lauritzen M

更新日期：1987-08-01 00:00:00